How do changes in ventilation rate, cardiac output

Ventilation-Perfusion Assignment Questions1. How do changes in ventilation rate, cardiac output, and dead space ventilationaffect alveolar PO2 and pulmonary venous PO2? Do these three factors have anadditive effect towards increasing or decreasing total oxygen delivery to tissues.Explain.Matlab files Vsensim and fdeadsens can be used as a guide for Qn #12. How can a change in mixed venous PO2 affect alveolar PO2 and total oxygendelivery to tissues?3. Consider three different metabolic rates for an average person, viz., resting, active,maximal activity. How should the ventilation and perfusion rates change undereach of these circumstances in order to ensure sufficient delivery of oxygen to thetissues? Would these rates also maintain sufficient saturation of blood in thepulmonary capillaries for each activity?4. What happens to total oxygen delivery to tissues if there is a decrease in deadspace ventilation? What other factor(s) could affect the oxygen delivery?5. The Matlab file VQ3levsimrun systematically varies the ventilation and perfusionrates in the different lung segments. Explain what happens to the partial pressureof oxygen in the alveoli and the concentration of oxygen in the alveoli for thedifferent lung segments in each case. Explain how the oxygen concentrations atthe left atrium (and in the systemic circuit) are affected by the variation in alveoliin different parts of the lung.