Glutathione (GTH) is a potent antioxidant found in our cells.
GTH is a tripeptide.
Its full name is γ-glutamylcysteinylglycine.
It contains an SH group, and these groups are reducing agents. They react with free radicals and other oxidizing agents to form disulfides.
2RSH + 2RO· → RS-SR + 2ROH
In glutathione, the product is glutathione disulfide, GSSG.
Main Role of Glutathione: Antioxidant
Glutathione is an essential component of the body’s natural defense system.
Viruses, bacteria, heavy metals, radiation, certain medications, and even the normal process of aging can all generate free-radicals. Glutathione reacts with and destroys these free radicals.
Other Functions of Glutathione
Maintenance of other endogenous antioxidants such as vitamins C and E in their reduced (active) forms
DNA synthesis and repair
Amino acid transport
Protein synthesis
Enzyme activation
Iron metabolism
Prostaglandin synthesis
Regulation of the nitric oxide cycle
Almost every system in the body can be affected by the state of the glutathione system. These include the immune system, the nervous system, the gastrointestinal system, and the lungs.
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