Microbiology : Course Scholar

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page 1- original Post with references

page 2- Icelene response

page 3- Jennifer response 

original post

In week 3, we are studying the Linnaeus classification system. Unfortunately, during the time of Linnaeus, a good way to classify viruses was not present. In fact, viruses get to have their own system of classification altogether in many ways, because they tether between alive and not alive. Most scientists consider viruses not alive, per definition. As intracellular parasites, a unique system of classification is worthy for the viruses in order to better understand them, how they replicate, what they infect and if they have the ability to become lysogenic. 

For this discussion, I want you to choose your favorite virus and address the questions below. Make sure to include the manner in which the virus is classified, what it infects, the type of life cycle and disease the virus causes.

Review the information available at NCBI Structure and Classification of Viruses
 

You will need to do some research to find your favorite virus to add additional information. Here is a list to help you choose.

Make sure to chose a different virus from your classmates.

Choose only ONE:

Topic 1. Chikungunya virus http://www.who.int/mediacentre/factsheets/fs327/en/

Topic 2. Varicelle-zoster virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC172899/pdf/090361.pdf

Topic 3. Zika virus http://ecdc.europa.eu/en/healthtopics/zika_virus_infection/Pages/index.aspx

Topic 4. Rabies virus http://www.ncbi.nlm.nih.gov/books/NBK8618/

Topic 5. Borna disease virus http://www.ncbi.nlm.nih.gov/pmc/articles/PMC88987/

Topic 6. Rubella virus http://www.who.int/mediacentre/factsheets/fs367/en/

Topic 7. Epstein-Barr virus http://www.cdc.gov/epstein-barr/index.html

Topic 8. Parvovirus (B19) Fifth disease (humans) http://www.cdc.gov/parvovirusB19/fifth-disease.html

Topic 9. Parvovirus (canines) http://www.vet.cornell.edu/baker/about/articles/CanineParvovirus.cfm

Topic 10. Feline Leukemia virus (cats) http://www.vet.cornell.edu/fhc/Health_Information/brochure_felv.cfm
 

Once you have reviewed this information, address the following questions;

What type of virus have you chosen (DNA or RNA)?
Is your virus single stranded or doubled stranded?
If RNA, is the strand + or -?
What species does the virus infect?
What are the life-cycle stages of the virus?
What disease does your virus cause?

____________________________

Student Responses

Icelene

Good Morning Everyone, I scanned through all of the following viruses listed below and I feel like the one that caught my eye the most and the one I have heard about ever since I was young was the Rabies Virus. The rabies virus has a more scientific name and that is Rhabdovirus, which I never knew. I remember being younger and my grandmother would always tell me not to touch stray animals because they have rabies, I thought it was just because she did not want me touching any and every animal because it could bare diseases. The rabies virus mainly effects animals and when humans come in contact and get bit by one who has the virus. It is stated in the passage linked to the rhabdovirus that humans who do not have any bite marks from an effected animal will rarely cause this virus in humans. The rabies virus that I have chosen is a RNA single stranded virus with a negative strand. The life cycle stages of this specific virus is a three step phase process, with the first phase being binding and entry to the cell by form of active transport. Then followed by uncoating, lastly the gathering of viral components and the release of the rabies virus particles. The virus Rhabdovirus is rabies and that is the disease, if this is not treated soon after one even thinks that they might be infected, it can become very deadly. Once this virus has reached the brain there is not much of anything that any medical doctors can do. -Ice

Jennifer 

Hello everyone,

I chose to do research over Feline Leukemia virus. I saw cat and got excited and decided to research over this interesting virus. 

The Feline Leukemia virus is RNA. It is contracted through saliva, nasal secretions, urine, feces, and the milk of infected cats. Other ways of transmission is from bite wounds or shared litter boxes and shared dishes. Mother cats may also spread the virus from before birth or through feeding of the milk. This virus is single stranded and also positive. As I mentioned before this virus infects cats or felines as biology calls them. The life cycle starts out as a retrovirus that infects the cells with enzymes called reverse transcriptase. This circular virus embeds itself into the cells it would like to infect. Homologous recombination occurs at the 3’ junctions and at the ACCCC 5’ junctions. This virus can lead to more serious issues such as anemia, lymphoma, or even death if the virus persists from three years. Anemia is when your red blood cells decrease. Lymphoma is a type of cancer. 

A few signs that suggest a cat is suffering from Feline Leukemia Virus are loss of appetite, persistent weight loss, pale gums, and constant bouts with diarrhea. 

Sadly there is not a specific treatment for this virus. Veterinarians tend to target certain problems rather than as a whole. Often time’s veterinarians will use antibiotics to treat bacterial infections. 

When I adopted my cat from the Nebraska Humane Society he had been tested for the virus and was thankfully negative. Experts say to keep your cat inside and if you do happen to adopt a stray off the street, be sure to have them tested by their veterinarian. 

-Jenny

Feline leukemia virus strain FRA. (n.d.). Retrieved from https://microbewiki.kenyon.edu/index.php/Feline_leukemia_virus_strain_FRA

Kornbreich, B. (2018, July 23). Feline Leukemia Virus. Retrieved from https://www2.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/feline-leukemia-virus

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